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The Antimicrobial Peptides Pharmaceuticals Company

Swift action

Nature's own defence mechanism

Stable, ultrabroad-spectrum antimicrobials, derived from bovine lactoferricin

Mode of action

LTX-109 is a synthetic, antimicrobial peptide which rapidly breaks down the cell membranes of microorganisms.

We have shown that LTX-109 is very effective at eliminating bacterial biofilms formed by Pseudomonas aeruginosa, in this case killing it at only four times the concentration needed to kill planktonic, non-biofilm bacteria. This level of efficacy is quite unheard of with most other antibiotics.

Prof. John Sigurd Svendsen

Rapid killing of Pathogens

LTX-109 acting on Staphylococcus aureus bacteria; Live (green) and dead (red). Time lapsing in minutes.

Wide action, unlikely development of resistance

Preclinical models have demonstrated that LTX-109 is strongly bactericidal, being equally effective against wild-type as well as drug-resistant bacteria such as MRSA. Because of its unique membrane-lysing mechanism of action, there is no cross-resistance to other drugs. It has also proven highly unlikely for bacteria to develop new resistance to the drug.

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