Posters and publications

Host Defence Peptides

Technology

Completed trials

Posters and publications

Pipeline

Posters – Clinical

Poster Nasal Decolonization
Poster Impetigo
Poster MRSA

Posters – Preclinical

Poster Antifungal
Evaluation of the In Vitro ADME Profile of LTX-109
Evaluation of the Preclinical Safety and Tolerability Profile of LTX-109
In-vitro Activity of LTX-109 against Vancomycin Intermediate (VISA)…
LTX-109 Demonstrates Rapid Membranolytic Activity against Escherichia coli and Staphylococcus aureus
LTX-109 is Active against CA-MRSA (USA300) and S. pyogenes in a Mouse Skin Infection Model
The Activity of LTX-109 Against a Range of Recent Gram Positive and Gram Negative Clinical Isolates
Poster Biofilm
LTX-109 publications

Isaksson et.al. A Synthetic Antimicrobial Peptidomimetic (LTX 109). Stereochemical Impact on Membrane Disruption

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The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner

Nilsson et.al. LTX-109 Is a Novel Agent for Nasal Decolonization of MethicillinResistant and -Sensitive Staphylococcus aureus

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The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner
In Vitro Activities of LTX-109, a Synthetic Antimicrobial Peptide, against Methicillin-Resistant, Vancomycin-Intermediate, Vancomycin- Resistant, Daptomycin-Nonsusceptible, and Linezolid-Nonsusceptible Staphylococcus aureus

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In Vitro Activities of LTX-109, a Synthetic Antimicrobial Peptide, against Methicillin-Resistant, Vancomycin-Intermediate, Vancomycin- Resistant, Daptomycin-Nonsusceptible, and Linezolid-Nonsusceptible Staphylococcus aureus
Postantibiotic effect and postantibiotic sub-MIC effect of LTX-109 and mupirocin on Staphylococcus aureus blood isolates

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Postantibiotic effect and postantibiotic sub-MIC effect of LTX-109 and mupirocin on Staphylococcus aureus blood isolates

The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner

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The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner

Haug et.al. The Medicinal Chemistry of Short Lactoferricin-Based Antibacterial Peptides

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The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner

Stensen et.al. Short Cationic Antimicrobial Peptides Display Superior Antifungal Activities toward Candidiasis and Onychomycosis in Comparison with Terbinafine and Amorolfine

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The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner

Svendsen et.al. Very Short and Stable Lactoferricin Derived Antimicrobial Peptides

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The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner
High in vitro antimicrobial activity of synthetic antimicrobial peptidomimetics against staphylococcal biofilms

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The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner
General publications
New Horizons to Survive in a Post-Antibiotics Era

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The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner
The Road from Host-Defense Peptides to a New Generation of Antimicrobial Drugs

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The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner
Small Molecular Antibacterial Peptoid Mimics: The Simpler the
Better!

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The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner
Antimicrobial peptides stage a comeback

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The Synthetic Amphipathic Peptidomimetic LTX109 Is a Potent Fungicide That Disturbs Plasma Membrane Integrity in a Sphingolipid Dependent Manner